Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity

Trained innate immunity fosters a sustained favorable response of myeloid cells to a secondary challenge, despite their short lifespan in circulation. We thus hypothesized that trained immunity acts via modulation of hematopoietic stem and progenitor cells (HSPCs). Administration of β-glucan (protot...

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Detalles Bibliográficos
Autores principales: Mitroulis, Ioannis, Ruppova, Klara, Wang, Baomei, Chen, Lan-Sun, Grzybek, Michal, Grinenko, Tatyana, Eugster, Anne, Troullinaki, Maria, Palladini, Alessandra, Kourtzelis, Ioannis, Chatzigeorgiou, Antonios, Schlitzer, Andreas, Beyer, Marc, Joosten, Leo A.B., Isermann, Berend, Lesche, Mathias, Petzold, Andreas, Simons, Kai, Henry, Ian, Dahl, Andreas, Schultze, Joachim L., Wielockx, Ben, Zamboni, Nicola, Mirtschink, Peter, Coskun, Ünal, Hajishengallis, George, Netea, Mihai G., Chavakis, Triantafyllos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766828/
https://www.ncbi.nlm.nih.gov/pubmed/29328910
http://dx.doi.org/10.1016/j.cell.2017.11.034

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