IL-33/ST2 signaling contributes to radicular pain by modulating MAPK and NF-κB activation and inflammatory mediator expression in the spinal cord in rat models of noncompressive lumber disk herniation

BACKGROUND: Immune and inflammatory responses occurring in the spinal cord play a pivotal role in the progression of radicular pain caused by intervertebral disk herniation. Interleukin-33 (IL-33) orchestrates inflammatory responses in a wide range of inflammatory and autoimmune disorders of the ner...

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Detalles Bibliográficos
Autores principales: Huang, Si-Jian, Yan, Jian-Qin, Luo, Hui, Zhou, Lu-Yao, Luo, Jian-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766999/
https://www.ncbi.nlm.nih.gov/pubmed/29329586
http://dx.doi.org/10.1186/s12974-017-1021-4

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