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Epigenetic alterations in TRAMP mice: epigenome DNA methylation profiling using MeDIP-seq

PURPOSE: We investigated the genomic DNA methylation profile of prostate cancer in transgenic adenocarcinoma of the mouse prostate (TRAMP) cancer model and to analyze the crosstalk among targeted genes and the related functional pathways. METHODS: Prostate DNA samples from 24-week-old TRAMP and C57B...

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Detalles Bibliográficos
Autores principales: Li, Wenji, Huang, Ying, Sargsyan, Davit, Khor, Tin Oo, Guo, Yue, Shu, Limin, Yang, Anne Yuqing, Zhang, Chengyue, Paredes-Gonzalez, Ximena, Verzi, Michael, Hart, Ronald P., Kong, Ah-Ng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767006/
https://www.ncbi.nlm.nih.gov/pubmed/29344347
http://dx.doi.org/10.1186/s13578-018-0201-y