Human umbilical cord mesenchymal stem cell conditioned medium attenuates renal fibrosis by reducing inflammation and epithelial-to-mesenchymal transition via the TLR4/NF-κB signaling pathway in vivo and in vitro

BACKGROUND: Renal fibrosis is characterized by infiltration of interstitial inflammatory cells and release of inflammatory mediators, activation and proliferation of fibroblasts, and deposition of excessive extracellular matrix (ECM). The aim of this study was to evaluate the effect of human umbilic...

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Detalles Bibliográficos
Autores principales: Liu, Bo, Ding, Fengxia, Hu, Dong, Zhou, Yu, Long, Chunlan, Shen, Lianju, Zhang, Yuanyuan, Zhang, Deying, Wei, Guanghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767037/
https://www.ncbi.nlm.nih.gov/pubmed/29329595
http://dx.doi.org/10.1186/s13287-017-0760-6

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