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Microfluidic co-culture of pancreatic tumor spheroids with stellate cells as a novel 3D model for investigation of stroma-mediated cell motility and drug resistance

BACKGROUND: Pancreatic stellate cells (PSCs), a major component of the tumor microenvironment in pancreatic cancer, play roles in cancer progression as well as drug resistance. Culturing various cells in microfluidic (microchannel) devices has proven to be a useful in studying cellular interactions...

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Detalles Bibliográficos
Autores principales:	Lee, Ji-Hyun, Kim, Seul-Ki, Khawar, Iftikhar Ali, Jeong, Su-Yeong, Chung, Seok, Kuh, Hyo-Jeong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767067/ https://www.ncbi.nlm.nih.gov/pubmed/29329547 http://dx.doi.org/10.1186/s13046-017-0654-6

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