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Multiple Extramedullary Plasmacytoma in a Setting of Complete Bone Marrow Remission: Food for Thought
Extramedullary plasmacytoma as a mode of relapse in multiple myeloma (MM) is unusual. Current recommendations do not incorporate the routine use of 18-fluorodeoxyglucose positron emission tomography-computed tomography (FDG PET/CT) imaging prior to haematopoietic stem cell transplant (HSCT) in MM. W...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Tehran University of Medical Sciences, Hematology-Oncology and Stem Cell Transplantation Research Center
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767287/ https://www.ncbi.nlm.nih.gov/pubmed/29340123 |
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author | Preety, Negi Alice, Kingsley Pamela Chinnu, Jomi Amrith, Mathew Sneha, George Vivek, Immanuel Abraham, Abraham Puliyelil |
author_facet | Preety, Negi Alice, Kingsley Pamela Chinnu, Jomi Amrith, Mathew Sneha, George Vivek, Immanuel Abraham, Abraham Puliyelil |
author_sort | Preety, Negi |
collection | PubMed |
description | Extramedullary plasmacytoma as a mode of relapse in multiple myeloma (MM) is unusual. Current recommendations do not incorporate the routine use of 18-fluorodeoxyglucose positron emission tomography-computed tomography (FDG PET/CT) imaging prior to haematopoietic stem cell transplant (HSCT) in MM. We report a case of relapsed MM with complete remission as per IMWG criteria. In the interim period, before the HSCT, the patient had localizing neurological signs and symptoms attributed to multiple extramedullary plasmacytomas. The uniqueness of this case is that this patient after complete marrow remission with no obvious external masses had unexpected, symptomatic multiple extramedullary plasmacytomas. This case illustrates the need for integration of FDG PET/CT imaging into routine pre-HSCT investigations in relapsed MM to prevent missing any asymptomatic extramedullary plasmacytomas. |
format | Online Article Text |
id | pubmed-5767287 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Tehran University of Medical Sciences, Hematology-Oncology and Stem Cell Transplantation Research Center |
record_format | MEDLINE/PubMed |
spelling | pubmed-57672872018-01-16 Multiple Extramedullary Plasmacytoma in a Setting of Complete Bone Marrow Remission: Food for Thought Preety, Negi Alice, Kingsley Pamela Chinnu, Jomi Amrith, Mathew Sneha, George Vivek, Immanuel Abraham, Abraham Puliyelil Int J Hematol Oncol Stem Cell Res Case Report Extramedullary plasmacytoma as a mode of relapse in multiple myeloma (MM) is unusual. Current recommendations do not incorporate the routine use of 18-fluorodeoxyglucose positron emission tomography-computed tomography (FDG PET/CT) imaging prior to haematopoietic stem cell transplant (HSCT) in MM. We report a case of relapsed MM with complete remission as per IMWG criteria. In the interim period, before the HSCT, the patient had localizing neurological signs and symptoms attributed to multiple extramedullary plasmacytomas. The uniqueness of this case is that this patient after complete marrow remission with no obvious external masses had unexpected, symptomatic multiple extramedullary plasmacytomas. This case illustrates the need for integration of FDG PET/CT imaging into routine pre-HSCT investigations in relapsed MM to prevent missing any asymptomatic extramedullary plasmacytomas. Tehran University of Medical Sciences, Hematology-Oncology and Stem Cell Transplantation Research Center 2017-10-01 /pmc/articles/PMC5767287/ /pubmed/29340123 Text en Copyright : © International Journal of Hematology-Oncology and Stem Cell Research & Tehran University of Medical Sciences This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Preety, Negi Alice, Kingsley Pamela Chinnu, Jomi Amrith, Mathew Sneha, George Vivek, Immanuel Abraham, Abraham Puliyelil Multiple Extramedullary Plasmacytoma in a Setting of Complete Bone Marrow Remission: Food for Thought |
title | Multiple Extramedullary Plasmacytoma in a Setting of Complete Bone Marrow Remission: Food for Thought |
title_full | Multiple Extramedullary Plasmacytoma in a Setting of Complete Bone Marrow Remission: Food for Thought |
title_fullStr | Multiple Extramedullary Plasmacytoma in a Setting of Complete Bone Marrow Remission: Food for Thought |
title_full_unstemmed | Multiple Extramedullary Plasmacytoma in a Setting of Complete Bone Marrow Remission: Food for Thought |
title_short | Multiple Extramedullary Plasmacytoma in a Setting of Complete Bone Marrow Remission: Food for Thought |
title_sort | multiple extramedullary plasmacytoma in a setting of complete bone marrow remission: food for thought |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767287/ https://www.ncbi.nlm.nih.gov/pubmed/29340123 |
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