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SIRT1/PGC-1α Signaling Promotes Mitochondrial Functional Recovery and Reduces Apoptosis after Intracerebral Hemorrhage in Rats

Silent information regulator 1 (SIRT1) exerts neuroprotection in many neurodegenerative diseases. However, it is not clear if SIRT1 has protective effects after intracerebral hemorrhage (ICH)-induced brain injury in rats. Thus, our goal was to examine the influence of SIRT1 on ICH injuries and any u...

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Detalles Bibliográficos
Autores principales: Zhou, Yang, Wang, Shaohua, Li, Yixin, Yu, Shanshan, Zhao, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767311/
https://www.ncbi.nlm.nih.gov/pubmed/29375306
http://dx.doi.org/10.3389/fnmol.2017.00443