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The GlyT1 Inhibitor Bitopertin Ameliorates Allodynia and Hyperalgesia in Animal Models of Neuropathic and Inflammatory Pain

Background: Chronic pain conditions are difficult to treat and the therapeutic outcome is frequently unsatisfactory. Changes in excitation/inhibition balance within the dorsal horn contribute to the establishment and persistence of chronic pain. Thus, facilitation of inhibitory neurotransmission is...

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Detalles Bibliográficos
Autores principales:	Armbruster, Anja, Neumann, Elena, Kötter, Valentin, Hermanns, Henning, Werdehausen, Robert, Eulenburg, Volker
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767717/ https://www.ncbi.nlm.nih.gov/pubmed/29375301 http://dx.doi.org/10.3389/fnmol.2017.00438

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