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IDH1R132H Promotes Malignant Transformation of Benign Prostatic Epithelium by Dysregulating MicroRNAs: Involvement of IGF1R-AKT/STAT3 Signaling Pathway

Risk stratification using molecular features could potentially help distinguish indolent from aggressive prostate cancer (PCa). Mutations in isocitrate dehydrogenase (IDH) acquire an abnormal enzymatic activity, resulting in the production of 2-hydroxyglutarate and alterations in cellular metabolism...

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Detalles Bibliográficos
Autores principales:	Zhang, Lili, Qi, Mei, Feng, Tingting, Hu, Jing, Wang, Lin, Li, Xinjun, Gao, Wei, Liu, Hui, Jiao, Meng, Wu, Zhen, Bai, Xinnuo, Bie, Yifan, Liu, Long, Han, Bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2018
Materias:	Original article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767912/ https://www.ncbi.nlm.nih.gov/pubmed/29331887 http://dx.doi.org/10.1016/j.neo.2017.12.001

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