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Mecambridine induces potent cytotoxic effects, autophagic cell death and modulation of the mTOR/PI3K/Akt signaling pathway in HSC-3 oral squamous cell carcinoma cells

Plant secondary metabolites including alkaloids, demonstrate a complex diversity in their molecular scaffolds and exhibit tremendous pharmacological potential as anti-cancerous therapeutics. The present study aimed to evaluate the anticancer activity of a natural alkaloid, mecambridine, against huma...

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Detalles Bibliográficos
Autores principales:	Lin, Na, Li, Zhiping, Wang, Deli, Zheng, Kewen, Wu, Yiyan, Wang, Huiqi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768076/ https://www.ncbi.nlm.nih.gov/pubmed/29422960 http://dx.doi.org/10.3892/ol.2017.7321

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