MicroRNA-300 Regulates the Ubiquitination of PTEN through the CRL4B(DCAF13) E3 Ligase in Osteosarcoma Cells

Cullins, critical members of the cullin-RING ubiquitin ligases (CRLs), are often aberrantly expressed in different cancers. However, the underlying mechanisms regarding aberrant expression of these cullins and the specific substrates of CRLs in different cancers are mostly unknown. Here, we demonstr...

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Detalles Bibliográficos
Autores principales: Chen, Zhi, Zhang, Wei, Jiang, Kaibiao, Chen, Bin, Wang, Kun, Lao, Lifeng, Hou, Canglong, Wang, Fei, Zhang, Caiguo, Shen, Hongxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768150/
https://www.ncbi.nlm.nih.gov/pubmed/29499938
http://dx.doi.org/10.1016/j.omtn.2017.12.010

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