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Targeting polyelectrolyte networks in purulent body fluids to modulate bactericidal properties of some antibiotics
The response of the human immune system to most bacterial infections results in accumulation of neutrophils at infection sites that release a significant quantity of DNA and F-actin. Both are negatively charged polyelectrolytes that can interact with positively charged host defense molecules such as...
Autores principales: | Bucki, Robert, Durnaś, Bonita, Wątek, Marzena, Piktel, Ewelina, Cruz, Katrina, Wolak, Przemysław, Savage, Paul B, Janmey, Paul A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768182/ https://www.ncbi.nlm.nih.gov/pubmed/29391814 http://dx.doi.org/10.2147/IDR.S145337 |
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