Identification of MALT1 as both a prognostic factor and a potential therapeutic target of regorafenib in cholangiocarcinoma patients

Intrahepatic cholangiocarcinoma (CCA) is an aggressive cancer that lacks an effective targeted therapy. Here, we assessed the therapeutic efficacy of regorafenib in CCA, as well as elucidated its underlying mechanism. We first demonstrated that regorafenib not only inhibited growth but also induced...

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Detalles Bibliográficos
Autores principales: Yeh, Chun-Nan, Chang, Yu-Chan, Su, Yeu, Shin-Shian Hsu, Dennis, Cheng, Chi-Tung, Wu, Ren-Chin, Chung, Yi-Hsiu, Chiang, Kun-Chun, Yeh, Ta-Sen, Lu, Meng-Lun, Liu, Chun-Yu, Mu-Hsin Chang, Peter, Chen, Ming-Han, Huang, Chi-Ying F., Hsiao, Michael, Chen, Ming-Huang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768338/
https://www.ncbi.nlm.nih.gov/pubmed/29371921
http://dx.doi.org/10.18632/oncotarget.23049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768338/
https://www.ncbi.nlm.nih.gov/pubmed/29371921
http://dx.doi.org/10.18632/oncotarget.23049

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