Helicobacter pylori CagA protein activates Akt and attenuates chemotherapeutics-induced apoptosis in gastric cancer cells

Infection with cagA-positive Helicobacter pylori is associated with a higher risk of gastric cancer. The cagA gene product, CagA, is translocated into gastric epithelial cells and perturbs host cellular biological functions. Etoposide, a topoisomerase II inhibitor widely used to couple DNA damage to...

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Detalles Bibliográficos
Autores principales: Lan, Keng-Hsueh, Lee, Wei-Ping, Wang, Yu-Shan, Liao, Shi-Xian, Lan, Keng-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768339/
https://www.ncbi.nlm.nih.gov/pubmed/29371922
http://dx.doi.org/10.18632/oncotarget.23050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768339/
https://www.ncbi.nlm.nih.gov/pubmed/29371922
http://dx.doi.org/10.18632/oncotarget.23050

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