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Progesterone and calcitriol reduce invasive potential of endometrial cancer cells by targeting ARF6, NEDD9 and MT1-MMP

Previously, we have demonstrated that progesterone and calcitriol synergistically inhibit growth of endometrial and ovarian cancer by enhancing apoptosis and causing cell cycle arrest. Metastasis is the main reason of mortality in cancer patients. Activation of ADP-Ribosylation Factor 6 (ARF6), Neur...

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Detalles Bibliográficos
Autores principales: Waheed, Sana, Dorjbal, Batsukh, Hamilton, Chad A., Maxwell, G. Larry, Rodriguez, Gustavo C., Syed, Viqar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768348/
https://www.ncbi.nlm.nih.gov/pubmed/29371931
http://dx.doi.org/10.18632/oncotarget.22745