Truncated protein tyrosine phosphatase receptor type O suppresses AKT signaling through IQ motif containing GTPase activating protein 1 and confers sensitivity to bortezomib in multiple myeloma

Proteasome inhibitors are an important part of our chemotherapeutic armamentarium against multiple myeloma, but the vast majority of patients eventually develop drug-resistant disease through incompletely understood mechanisms. Comparison of gene expression profiles (GEPs) of bortezomib-resistant (B...

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Detalles Bibliográficos
Autores principales: Wang, Hua, Baladandayuthapani, Veerabhadran, Wang, Zhiqiang, Lin, Heather, Berkova, Zuzana, Davis, Richard E., Yang, Lin, Orlowski, Robert Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768369/
https://www.ncbi.nlm.nih.gov/pubmed/29371952
http://dx.doi.org/10.18632/oncotarget.23017

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