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CD44 drives aggressiveness and chemoresistance of a metastatic human osteosarcoma xenograft model
BACKGROUND: Osteosarcoma is the most common primary malignant bone tumor with a 5 year survival rate of up to 70%. However, patients with metastatic disease have still a very poor prognosis. Osteosarcoma metastasis models are essential to develop novel treatment strategies for advanced disease. METH...
Autores principales: | Mayr, Lisa, Pirker, Christine, Lötsch, Daniela, Van Schoonhoven, Sushilla, Windhager, Reinhard, Englinger, Bernhard, Berger, Walter, Kubista, Bernd |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768389/ https://www.ncbi.nlm.nih.gov/pubmed/29371972 http://dx.doi.org/10.18632/oncotarget.23125 |
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