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CD44 drives aggressiveness and chemoresistance of a metastatic human osteosarcoma xenograft model

BACKGROUND: Osteosarcoma is the most common primary malignant bone tumor with a 5 year survival rate of up to 70%. However, patients with metastatic disease have still a very poor prognosis. Osteosarcoma metastasis models are essential to develop novel treatment strategies for advanced disease. METH...

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Detalles Bibliográficos
Autores principales: Mayr, Lisa, Pirker, Christine, Lötsch, Daniela, Van Schoonhoven, Sushilla, Windhager, Reinhard, Englinger, Bernhard, Berger, Walter, Kubista, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768389/
https://www.ncbi.nlm.nih.gov/pubmed/29371972
http://dx.doi.org/10.18632/oncotarget.23125

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