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17-β-Estradiol induces spreading depression and pain behavior in alert female rats

AIMS: Test the putative contribution of 17-β-estradiol in the development of spreading depression (SD) events and head pain in awake, non-restrained rats. MAIN METHODS: Female, Sprague-Dawley rats were intact or underwent ovariectomy followed one week later by surgery to place electrodes onto the du...

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Detalles Bibliográficos
Autores principales: Sandweiss, Alexander J., Cottier, Karissa E., McIntosh, Mary I., Dussor, Gregory, Davis, Thomas P., Vanderah, Todd W., Largent-Milnes, Tally M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768390/
https://www.ncbi.nlm.nih.gov/pubmed/29371973
http://dx.doi.org/10.18632/oncotarget.23141