Cargando…

Insulin and novel thioglycosides exert suppressive effect on human breast and colon carcinoma cells

The rationale for the implementation of novel therapies should be based on hallmarks of cancer. Two novel compounds labelled as thioglycoside A and B were designed and evaluated on breast and colon cancer cell lines. We assessed their cytotoxic effect after sensitizing cancer cells with insulin. In...

Descripción completa

Detalles Bibliográficos
Autores principales:	Agrawal, Siddarth, Wozniak, Marta, Luc, Mateusz, Walaszek, Kinga, Pielka, Ewa, Szeja, Wieslaw, Pastuch-Gawolek, Gabriela, Gamian, Andrzej, Ziolkowski, Piotr
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768394/ https://www.ncbi.nlm.nih.gov/pubmed/29371977 http://dx.doi.org/10.18632/oncotarget.23170

Ejemplares similares

Overcoming Hypoxia-Induced Chemoresistance in Cancer Using a Novel Glycoconjugate of Methotrexate
por: Woźniak, Marta, et al.
Publicado: (2020)

In Vitro and In Vivo Efficacy of a Novel Glucose–Methotrexate Conjugate in Targeted Cancer Treatment
por: Woźniak, Marta, et al.
Publicado: (2021)

The Effect of a New Glucose–Methotrexate Conjugate on Acute Lymphoblastic Leukemia and Non-Hodgkin’s Lymphoma Cell Lines
por: Woźniak, Marta, et al.
Publicado: (2021)

Novel Uridine Glycoconjugates, Derivatives of 4-Aminophenyl 1-Thioglycosides, as Potential Antiviral Compounds
por: Krol, Ewelina, et al.
Publicado: (2018)

Insulin enhancement of the antitumor activity of chemotherapeutic agents in colorectal cancer is linked with downregulating PIK3CA and GRB2
por: Agrawal, Siddarth, et al.
Publicado: (2019)

Synthesis and Preliminary Evaluation of Biological Activity of Glycoconjugates Analogues of Acyclic Uridine Derivatives
por: Komor, Roman, et al.
Publicado: (2018)

Glycoconjugation of Quinoline Derivatives Using the C-6 Position in Sugars as a Strategy for Improving the Selectivity and Cytotoxicity of Functionalized Compounds
por: Domińska, Monika, et al.
Publicado: (2022)

6-Shogaol enhances the anticancer effect of 5-fluorouracil, oxaliplatin, and irinotecan via increase of apoptosis and autophagy in colon cancer cells in hypoxic/aglycemic conditions
por: Woźniak, Marta, et al.
Publicado: (2020)

A Small Sugar Molecule with Huge Potential in Targeted Cancer Therapy
por: Pastuch-Gawołek, Gabriela, et al.
Publicado: (2023)

The melibiose-derived glycation product mimics a unique epitope present in human and animal tissues
por: Staniszewska, Magdalena, et al.
Publicado: (2021)

Synthesis and Preliminary Evaluation of the Cytotoxicity of Potential Metabolites of Quinoline Glycoconjugates
por: Domińska, Monika, et al.
Publicado: (2022)

Shell-Sheddable Micelles Based on Poly(ethylene glycol)-hydrazone-poly[R,S]-3-hydroxybutyrate Copolymer Loaded with 8-Hydroxyquinoline Glycoconjugates as a Dual Tumor-Targeting Drug Delivery System
por: Domiński, Adrian, et al.
Publicado: (2022)

Activation of Thioglycosides with Copper(II) Bromide
por: Pooladian, Faranak, et al.
Publicado: (2022)

Anti-Hepatitis C Virus Activity of Uridine Derivatives of 2-Deoxy Sugars
por: Krol, Ewelina, et al.
Publicado: (2018)

8-Hydroxyquinoline Glycoconjugates Containing Sulfur at the Sugar Anomeric Position—Synthesis and Preliminary Evaluation of Their Cytotoxicity
por: Krawczyk, Monika, et al.
Publicado: (2020)

8-Hydroxyquinoline Glycoconjugates: Modifications in the Linker Structure and Their Effect on the Cytotoxicity of the Obtained Compounds
por: Krawczyk, Monika, et al.
Publicado: (2019)

Stimuli-Responsive Aliphatic Polycarbonate Nanocarriers for Tumor-Targeted Drug Delivery
por: Domiński, Adrian, et al.
Publicado: (2020)

Anti-Tick-Borne Encephalitis Virus Activity of Novel Uridine Glycoconjugates Containing Amide or/and 1,2,3-Triazole Moiety in the Linker Structure
por: Brzuska, Gabriela, et al.
Publicado: (2020)

Glycoconjugation of Betulin Derivatives Using Copper-Catalyzed 1,3-Dipolar Azido-Alkyne Cycloaddition Reaction and a Preliminary Assay of Cytotoxicity of the Obtained Compounds
por: Grymel, Mirosława, et al.
Publicado: (2020)

Selected nucleos(t)ide-based prescribed drugs and their multi-target activity
por: Pastuch-Gawołek, Gabriela, et al.
Publicado: (2019)

Physiological Hypoxia (Physioxia) Impairs the Early Adhesion of Single Lymphoma Cell to Marrow Stromal Cell and Extracellular Matrix. Optical Tweezers Study
por: Duś-Szachniewicz, Kamila, et al.
Publicado: (2018)

Novel Oxadiazole Thioglycosides as Potential Anti-Acinetobacter Agents
por: Akbari Dilmaghani, Karim, et al.
Publicado: (2016)

Thioglycosides Act as Metabolic Inhibitors of Bacterial Glycan Biosynthesis
por: Quintana, Isabella de la Luz, et al.
Publicado: (2023)

Synthesis of protected precursors of chitin oligosaccharides by electrochemical polyglycosylation of thioglycosides
por: Rahman, Md Azadur, et al.
Publicado: (2022)

Breast cancer risk in premalignant lesions: osteopontin splice variants indicate prognosis
por: Walaszek, Kinga, et al.
Publicado: (2018)

Protective effects of levamisole, acetylsalicylic acid, and α-tocopherol against dioxin toxicity measured as the expression of AhR and COX-2 in a chicken embryo model
por: Gostomska-Pampuch, Kinga, et al.
Publicado: (2016)

An Air- and Water-Stable Iodonium Salt Promoter for Facile Thioglycoside Activation
por: Chu, An-Hsiang Adam, et al.
Publicado: (2014)

Co-Delivery of 8-Hydroxyquinoline Glycoconjugates and Doxorubicin by Supramolecular Hydrogel Based on α-Cyclodextrin and pH-Responsive Micelles for Enhanced Tumor Treatment
por: Domiński, Adrian, et al.
Publicado: (2022)

Appel-reagent-mediated transformation of glycosyl hemiacetal derivatives into thioglycosides and glycosyl thiols
por: Ghosh, Tamashree, et al.
Publicado: (2013)

1,3-Dibromo-5,5-dimethylhydantoin as promoter for glycosylations using thioglycosides
por: Xu, Fei-Fei, et al.
Publicado: (2017)

Urea–hydrogen peroxide prompted the selective and controlled oxidation of thioglycosides into sulfoxides and sulfones
por: Singh, Adesh Kumar, et al.
Publicado: (2017)

Transition-metal-free synthesis of aryl 1-thioglycosides with arynes at room temperature
por: Liu, Yao, et al.
Publicado: (2021)

Novel triple mutant of an extremophilic glycosyl hydrolase enables the rapid synthesis of thioglycosides
por: Pillet, Lauriane, et al.
Publicado: (2022)

Synthetic Genistein Glycosides Inhibiting EGFR Phosphorylation Enhance the Effect of Radiation in HCT 116 Colon Cancer Cells
por: Gruca, Aleksandra, et al.
Publicado: (2014)

Antibodies against Escherichia coli O24 and O56 O-Specific Polysaccharides Recognize Epitopes in Human Glandular Epithelium and Nervous Tissue
por: Korzeniowska-Kowal, Agnieszka, et al.
Publicado: (2015)

Differentiation of single lymphoma primary cells and normal B-cells based on their adhesion to mesenchymal stromal cells in optical tweezers
por: Duś-Szachniewicz, Kamila, et al.
Publicado: (2019)

Design and synthesis of naphthalimide group-bearing thioglycosides as novel β-N-acetylhexosaminidases inhibitors
por: Shen, Shengqiang, et al.
Publicado: (2018)

A versatile glycosylation strategy via Au(iii) catalyzed activation of thioglycoside donors
por: Vibhute, Amol M., et al.
Publicado: (2016)

Sulfur and Azobenzenes, a Profitable Liaison: Straightforward Synthesis of Photoswitchable Thioglycosides with Tunable Properties
por: Berry, Jonathan, et al.
Publicado: (2022)

Transcutaneous Electrical Acupoint Stimulation Reduces Postoperative Analgesic Requirement in Patients Undergoing Inguinal Hernia Repair: A Randomized, Placebo-Controlled Study
por: Szmit, Mateusz, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ro2i9it3a2ulvrjvmum44qsgh8