Identification and validation of colorectal neoplasia-specific methylation biomarkers based on CTCF-binding sites

To date, the sensitivity of currently available biomarkers based on the methylation of gene promoters is suboptimal for detecting adenomas and early-stage colorectal cancer (CRC). We aimed to develop biomarkers with methylated DNA binding sites of the multifunctional transcriptional factor CTCF for...

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Detalles Bibliográficos
Autores principales: Liu, Jiang, Ding, Zhaoli, Li, Guimei, Tang, Li, Xu, Yu, Luo, Huayou, Yi, Jinhua, Lu, Youwang, Mao, Rui, Nan, Qiong, Ren, Li, Zhang, Tong, Wang, Kunhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768395/
https://www.ncbi.nlm.nih.gov/pubmed/29371978
http://dx.doi.org/10.18632/oncotarget.23172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768395/
https://www.ncbi.nlm.nih.gov/pubmed/29371978
http://dx.doi.org/10.18632/oncotarget.23172

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