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Identification and validation of colorectal neoplasia-specific methylation biomarkers based on CTCF-binding sites
To date, the sensitivity of currently available biomarkers based on the methylation of gene promoters is suboptimal for detecting adenomas and early-stage colorectal cancer (CRC). We aimed to develop biomarkers with methylated DNA binding sites of the multifunctional transcriptional factor CTCF for...
Autores principales: | Liu, Jiang, Ding, Zhaoli, Li, Guimei, Tang, Li, Xu, Yu, Luo, Huayou, Yi, Jinhua, Lu, Youwang, Mao, Rui, Nan, Qiong, Ren, Li, Zhang, Tong, Wang, Kunhua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768395/ https://www.ncbi.nlm.nih.gov/pubmed/29371978 http://dx.doi.org/10.18632/oncotarget.23172 |
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