Augmentation of hypoxia-inducible factor-1-alpha in reinfused blood cells enhances diabetic ischemic wound closure in mice

Diabetes-associated dysfunction in angiogenesis predominantly contributes to impairment of wound closure, but a role of hypoxia-inducible factor 1 alpha (HIF-1a) in the process remain poorly understood. Here, we examined whether expression of HIF-1a in re-infused blood cells may improve the diabetic...

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Detalles Bibliográficos
Autores principales: Wang, Huan, Feng, Yufeng, Jin, Xiaoju, Xia, Rong, Cheng, Yong, Liu, Xiaoqian, Zhu, Nana, Zhou, Xun, Yin, Lei, Guo, Jianrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768400/
https://www.ncbi.nlm.nih.gov/pubmed/29371983
http://dx.doi.org/10.18632/oncotarget.23214

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