The effect of an improvement of experience and training in extracorporeal membrane oxygenation management on clinical outcomes
BACKGROUND/AIMS: The use of extracorporeal membrane oxygenation (ECMO) is spreading rapidly, with successful procedures reported in the ECMO for Severe Adult Respiratory failure (CESAR) trial and treatment of the H1N1 pandemic. However, ECMO is associated with a high mortality rate. This study aimed...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Association of Internal Medicine
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768527/ https://www.ncbi.nlm.nih.gov/pubmed/27017393 http://dx.doi.org/10.3904/kjim.2015.027 |
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author | Kim, Go-Woon Koh, Younsuck Lim, Chae-Man Huh, Jin Won Jung, Sung Ho Kim, Joon Bum Hong, Sang-Bum |
author_facet | Kim, Go-Woon Koh, Younsuck Lim, Chae-Man Huh, Jin Won Jung, Sung Ho Kim, Joon Bum Hong, Sang-Bum |
author_sort | Kim, Go-Woon |
collection | PubMed |
description | BACKGROUND/AIMS: The use of extracorporeal membrane oxygenation (ECMO) is spreading rapidly, with successful procedures reported in the ECMO for Severe Adult Respiratory failure (CESAR) trial and treatment of the H1N1 pandemic. However, ECMO is associated with a high mortality rate. This study aimed to show that increased experience and improved teamwork through education may reduce the mortality rate associated with ECMO. METHODS: A retrospective study was performed. Data were collected from January 1, 2009, to December 31, 2011. The data were divided into two periods: 2009/2010 (period 1) and 2011 (period 2). The protocol and training program were applied during period 2. RESULTS: Seventy-six patients were included. The most common disease requiring ECMO support was pneumonia (43.4%). ECMO was applied within 7 days in 76.3% of patients. The primary outcomes, such as Intensive Care Unit (ICU) and hospital mortality rates, were higher during period 1 (91.3%) than period 2 (66.7%, p = 0.013). A multivariate analysis revealed that ECMO weaning failure was the only factor associated with ICU and hospital mortality (ICU mortality: hazard ratio [HR], 11.349; 95% confidence interval [CI], 1.281 to 100.505; p = 0.029; hospital mortality: HR, 17.976; 95% CI, 2.263 to 142.777; p = 0.006). CONCLUSIONS: The mortality rate associated with the ECMO procedure decreased following the ECMO training program. However, applying the training program to ECMO management is not an independent factor for the mortality rate. Further studies should be performed to help reduce the mortality rate associated with ECMO. |
format | Online Article Text |
id | pubmed-5768527 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | The Korean Association of Internal Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-57685272018-01-19 The effect of an improvement of experience and training in extracorporeal membrane oxygenation management on clinical outcomes Kim, Go-Woon Koh, Younsuck Lim, Chae-Man Huh, Jin Won Jung, Sung Ho Kim, Joon Bum Hong, Sang-Bum Korean J Intern Med Original Article BACKGROUND/AIMS: The use of extracorporeal membrane oxygenation (ECMO) is spreading rapidly, with successful procedures reported in the ECMO for Severe Adult Respiratory failure (CESAR) trial and treatment of the H1N1 pandemic. However, ECMO is associated with a high mortality rate. This study aimed to show that increased experience and improved teamwork through education may reduce the mortality rate associated with ECMO. METHODS: A retrospective study was performed. Data were collected from January 1, 2009, to December 31, 2011. The data were divided into two periods: 2009/2010 (period 1) and 2011 (period 2). The protocol and training program were applied during period 2. RESULTS: Seventy-six patients were included. The most common disease requiring ECMO support was pneumonia (43.4%). ECMO was applied within 7 days in 76.3% of patients. The primary outcomes, such as Intensive Care Unit (ICU) and hospital mortality rates, were higher during period 1 (91.3%) than period 2 (66.7%, p = 0.013). A multivariate analysis revealed that ECMO weaning failure was the only factor associated with ICU and hospital mortality (ICU mortality: hazard ratio [HR], 11.349; 95% confidence interval [CI], 1.281 to 100.505; p = 0.029; hospital mortality: HR, 17.976; 95% CI, 2.263 to 142.777; p = 0.006). CONCLUSIONS: The mortality rate associated with the ECMO procedure decreased following the ECMO training program. However, applying the training program to ECMO management is not an independent factor for the mortality rate. Further studies should be performed to help reduce the mortality rate associated with ECMO. The Korean Association of Internal Medicine 2018-01 2016-03-25 /pmc/articles/PMC5768527/ /pubmed/27017393 http://dx.doi.org/10.3904/kjim.2015.027 Text en Copyright © 2018 The Korean Association of Internal Medicine This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Kim, Go-Woon Koh, Younsuck Lim, Chae-Man Huh, Jin Won Jung, Sung Ho Kim, Joon Bum Hong, Sang-Bum The effect of an improvement of experience and training in extracorporeal membrane oxygenation management on clinical outcomes |
title | The effect of an improvement of experience and training in extracorporeal membrane oxygenation management on clinical outcomes |
title_full | The effect of an improvement of experience and training in extracorporeal membrane oxygenation management on clinical outcomes |
title_fullStr | The effect of an improvement of experience and training in extracorporeal membrane oxygenation management on clinical outcomes |
title_full_unstemmed | The effect of an improvement of experience and training in extracorporeal membrane oxygenation management on clinical outcomes |
title_short | The effect of an improvement of experience and training in extracorporeal membrane oxygenation management on clinical outcomes |
title_sort | effect of an improvement of experience and training in extracorporeal membrane oxygenation management on clinical outcomes |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768527/ https://www.ncbi.nlm.nih.gov/pubmed/27017393 http://dx.doi.org/10.3904/kjim.2015.027 |
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