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Metabolic Linkage and Correlations to Storage Capacity in Erythrocytes from Glucose 6-Phosphate Dehydrogenase-Deficient Donors

OBJECTIVE: In glucose 6-phosphate dehydrogenase (G6PD) deficiency, decreased NADPH regeneration in the pentose phosphate pathway and subnormal levels of reduced glutathione result in insufficient antioxidant defense, increased susceptibility of red blood cells (RBCs) to oxidative stress, and acute h...

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Detalles Bibliográficos
Autores principales: Reisz, Julie A., Tzounakas, Vassilis L., Nemkov, Travis, Voulgaridou, Artemis I., Papassideri, Issidora S., Kriebardis, Anastasios G., D’Alessandro, Angelo, Antonelou, Marianna H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768619/
https://www.ncbi.nlm.nih.gov/pubmed/29376053
http://dx.doi.org/10.3389/fmed.2017.00248