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Metabolic Linkage and Correlations to Storage Capacity in Erythrocytes from Glucose 6-Phosphate Dehydrogenase-Deficient Donors
OBJECTIVE: In glucose 6-phosphate dehydrogenase (G6PD) deficiency, decreased NADPH regeneration in the pentose phosphate pathway and subnormal levels of reduced glutathione result in insufficient antioxidant defense, increased susceptibility of red blood cells (RBCs) to oxidative stress, and acute h...
Autores principales: | Reisz, Julie A., Tzounakas, Vassilis L., Nemkov, Travis, Voulgaridou, Artemis I., Papassideri, Issidora S., Kriebardis, Anastasios G., D’Alessandro, Angelo, Antonelou, Marianna H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768619/ https://www.ncbi.nlm.nih.gov/pubmed/29376053 http://dx.doi.org/10.3389/fmed.2017.00248 |
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