Pediatric Anaplastic Embryonal Rhabdomyosarcoma: Targeted Therapy Guided by Genetic Analysis and a Patient-Derived Xenograft Study

Therapy for rhabdomyosarcoma (RMS) has generally been limited to combinations of conventional cytotoxic agents similar to regimens originally developed in the late 1960s. Recently, identification of molecular alterations through next-generation sequencing of individual tumor specimens has facilitate...

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Detalles Bibliográficos
Autores principales: Cramer, Stuart L., Miller, Aubrey L., Pressey, Joseph G., Gamblin, Tracy L., Beierle, Elizabeth A., Kulbersh, Brian D., Garcia, Patrick L., Council, Leona N., Radhakrishnan, Rupa, Hendrix, Skyler V., Kelly, David R., Watts, Raymond G., Yoon, Karina J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768639/
https://www.ncbi.nlm.nih.gov/pubmed/29376028
http://dx.doi.org/10.3389/fonc.2017.00327

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