Differential roles of Na(V)1.2 and Na(V)1.6 in regulating neuronal excitability at febrile temperature and distinct contributions to febrile seizures

Dysregulation of voltage-gated sodium channels (VGSCs) is associated with multiple clinical disorders, including febrile seizures (FS). The contribution of different sodium channel subtypes to environmentally triggered seizures is not well understood. Here we demonstrate that somatic and axonal sodi...

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Detalles Bibliográficos
Autores principales: Ye, Mingyu, Yang, Jun, Tian, Cuiping, Zhu, Qiyu, Yin, Luping, Jiang, Shan, Yang, Mingpo, Shu, Yousheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768682/
https://www.ncbi.nlm.nih.gov/pubmed/29335582
http://dx.doi.org/10.1038/s41598-017-17344-8

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