Modulation of UVB-induced Carcinogenesis by Activation of Alternative DNA Repair Pathways

The molecular basis for ultraviolet (UV) light-induced nonmelanoma and melanoma skin cancers centers on cumulative genomic instability caused by inefficient DNA repair of dipyrimidine photoproducts. Inefficient DNA repair and subsequent translesion replication past these DNA lesions generate distinc...

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Detalles Bibliográficos
Autores principales: Sha, Yan, Vartanian, Vladimir, Owen, Nichole, Mengden Koon, Stephanie J., Calkins, Marcus J., Thompson, Courtney S., Mirafzali, Zahra, Mir, Sara, Goldsmith, Lisa E., He, Huaping, Luo, Chun, Brown, Scott M., Doetsch, Paul W., Kaempf, Andy, Lim, Jeong Y., McCullough, Amanda K., Lloyd, R. Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768739/
https://www.ncbi.nlm.nih.gov/pubmed/29335541
http://dx.doi.org/10.1038/s41598-017-17940-8

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