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High-resolution TADs reveal DNA sequences underlying genome organization in flies

Despite an abundance of new studies about topologically associating domains (TADs), the role of genetic information in TAD formation is still not fully understood. Here we use our software, HiCExplorer (hicexplorer.readthedocs.io) to annotate >2800 high-resolution (570 bp) TAD boundaries in Droso...

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Detalles Bibliográficos
Autores principales: Ramírez, Fidel, Bhardwaj, Vivek, Arrigoni, Laura, Lam, Kin Chung, Grüning, Björn A., Villaveces, José, Habermann, Bianca, Akhtar, Asifa, Manke, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768762/
https://www.ncbi.nlm.nih.gov/pubmed/29335486
http://dx.doi.org/10.1038/s41467-017-02525-w

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