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Monitoring single-cell gene regulation under dynamically controllable conditions with integrated microfluidics and software

Much is still not understood about how gene regulatory interactions control cell fate decisions in single cells, in part due to the difficulty of directly observing gene regulatory processes in vivo. We introduce here a novel integrated setup consisting of a microfluidic chip and accompanying analys...

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Detalles Bibliográficos
Autores principales: Kaiser, Matthias, Jug, Florian, Julou, Thomas, Deshpande, Siddharth, Pfohl, Thomas, Silander, Olin K., Myers, Gene, van Nimwegen, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768764/
https://www.ncbi.nlm.nih.gov/pubmed/29335514
http://dx.doi.org/10.1038/s41467-017-02505-0