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Alteration in Fluidity of Cell Plasma Membrane in Huntington Disease Revealed by Spectral Phasor Analysis

Huntington disease (HD) is a late-onset genetic neurodegenerative disorder caused by expansion of cytosine-adenine-guanine (CAG) trinucleotide in the exon 1 of the gene encoding the polyglutamine (polyQ). It has been shown that protein degradation and lipid metabolism is altered in HD. In many neuro...

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Detalles Bibliográficos
Autores principales: Sameni, Sara, Malacrida, Leonel, Tan, Zhiqun, Digman, Michelle A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768877/
https://www.ncbi.nlm.nih.gov/pubmed/29335600
http://dx.doi.org/10.1038/s41598-018-19160-0