Cargando…

O-GlcNAc on PKCζ Inhibits the FGF4-PKCζ-MEK-ERK1/2 Pathway via Inhibition of PKCζ Phosphorylation in Mouse Embryonic Stem Cells

Mouse embryonic stem cells (ESCs) differentiate into multiple cell types during organismal development. Fibroblast growth factor 4 (FGF4) signaling induces differentiation from ESCs via the phosphorylation of downstream molecules such as mitogen-activated protein kinase/extracellular signal-related...

Descripción completa

Detalles Bibliográficos
Autores principales: Miura, Taichi, Kume, Masahiko, Kawamura, Takeshi, Yamamoto, Kazuo, Hamakubo, Takao, Nishihara, Shoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768893/
https://www.ncbi.nlm.nih.gov/pubmed/29249667
http://dx.doi.org/10.1016/j.stemcr.2017.11.007