Cargando…

O-GlcNAc on PKCζ Inhibits the FGF4-PKCζ-MEK-ERK1/2 Pathway via Inhibition of PKCζ Phosphorylation in Mouse Embryonic Stem Cells

Mouse embryonic stem cells (ESCs) differentiate into multiple cell types during organismal development. Fibroblast growth factor 4 (FGF4) signaling induces differentiation from ESCs via the phosphorylation of downstream molecules such as mitogen-activated protein kinase/extracellular signal-related...

Descripción completa

Detalles Bibliográficos
Autores principales:	Miura, Taichi, Kume, Masahiko, Kawamura, Takeshi, Yamamoto, Kazuo, Hamakubo, Takao, Nishihara, Shoko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768893/ https://www.ncbi.nlm.nih.gov/pubmed/29249667 http://dx.doi.org/10.1016/j.stemcr.2017.11.007

Ejemplares similares

Association of PKCζ Expression with Clinicopathological Characteristics of Breast Cancer
por: Yin, Jian, et al.
Publicado: (2014)

PKC-ζ Aggravates Doxorubicin-Induced Cardiotoxicity by Inhibiting Wnt/β-Catenin Signaling
por: Cao, Yan-Jun, et al.
Publicado: (2022)

Specific involvement of atypical PKCζ/PKMζ in spinal persistent nociceptive processing following peripheral inflammation in rat
por: Marchand, Fabien, et al.
Publicado: (2011)

The Effect of SIN1 and Microtubules on Insulin Induced PKC ζ Activation
por: Yingying, Xiang, et al.
Publicado: (2017)

PKCζ and PKMζ are overexpressed in TCF3-rearranged paediatric acute lymphoblastic leukaemia and are associated with increased thiopurine sensitivity
por: Hartsink-Segers, S A, et al.
Publicado: (2015)

Down-regulation of PKCζ in renal cell carcinoma and its clinicopathological implications
por: Pu, Yeong-Shiau, et al.
Publicado: (2012)

PKCζ Mediates Breakdown of Outer Blood-Retinal Barriers in Diabetic Retinopathy
por: Omri, Samy, et al.
Publicado: (2013)

Analysis of PKC-ζ protein levels in normal and malignant breast tissue subtypes
por: Smalley, Tracess, et al.
Publicado: (2019)

Oncogenic PKC-ι activates Vimentin during epithelial-mesenchymal transition in melanoma; a study based on PKC-ι and PKC-ζ specific inhibitors
por: Ratnayake, Wishrawana S., et al.
Publicado: (2018)

The Atypical Protein Kinase C Small Molecule Inhibitor ζ-Stat, and Its Effects on Invasion Through Decreases in PKC-ζ Protein Expression
por: Smalley, Tracess, et al.
Publicado: (2020)

Spheciosterol Sulfates, PKCζ Inhibitors from a Philippine Sponge Spheciospongia sp.
por: Whitson, Emily L., et al.
Publicado: (2008)

Novel PKC-ζ to p47(phox) interaction is necessary for transformation from blebbishields
por: Jinesh, Goodwin G., et al.
Publicado: (2016)

Combination therapy of PKCζ and COX-2 inhibitors synergistically suppress melanoma metastasis
por: Zhou, Ping, et al.
Publicado: (2017)

PKCζ-Mitogen-Activated Protein Kinase Signaling Mediates Crotalphine-Induced Antinociception
por: de Freitas, Bárbara G., et al.
Publicado: (2021)

Clinical significance of atypical protein kinase C (PKCι and PKCζ) and its relationship with yes-associated protein in lung adenocarcinoma
por: Kim, Kyung-Hee, et al.
Publicado: (2019)

PKCζ mediates disturbed flow-induced endothelial apoptosis via p53 SUMOylation
por: Heo, Kyung-Sun, et al.
Publicado: (2011)

Chemoresistance and Cancer-Related Inflammation: Two Hallmarks of Cancer Connected by an Atypical Link, PKCζ
por: Rimessi, Alessandro, et al.
Publicado: (2013)

PKCζ and JNK signaling regulate radiation-induced compensatory proliferation in parotid salivary glands
por: Wong, Wen Yu, et al.
Publicado: (2019)

Glucose‐ or insulin resistance‐mediated β‐cell replication: PKCζ integrates the proliferative signaling
por: Shirakawa, Jun, et al.
Publicado: (2016)

PKCζ phosphorylates TRAF2 to protect against intestinal ischemia–reperfusion–induced injury
por: Zhou, Wei, et al.
Publicado: (2017)

Role of prelimbic cortex PKC and PKMζ in fear memory reconsolidation and persistence following reactivation
por: da Silva, Thiago Rodrigues, et al.
Publicado: (2020)

PEPCK-M recoups tumor cell anabolic potential in a PKC-ζ-dependent manner
por: Hyroššová, Petra, et al.
Publicado: (2021)

Correction to: Combination therapy of PKCζ and COX-2 inhibitors synergistically suppress melanoma metastasis
por: Zhou, Ping, et al.
Publicado: (2021)

PKCζ Phosphorylates SIRT6 to Mediate Fatty Acid β-Oxidation in Colon Cancer Cells
por: Gao, Tian, et al.
Publicado: (2018)

PKCζ facilitates lymphatic metastatic spread of prostate cancer cells in a mice xenograft model
por: Zang, Guangxiang, et al.
Publicado: (2019)

Piezoelectric effect stimulates the rearrangement of chondrogenic cells and alters ciliary orientation via atypical PKCζ
por: Lim, Jormay, et al.
Publicado: (2022)

G3BP1 regulates breast cancer cell proliferation and metastasis by modulating PKCζ
por: Liu, Shuang, et al.
Publicado: (2022)

HGF-Induced PKCζ Activation Increases Functional CXCR4 Expression in Human Breast Cancer Cells
por: Huang, Songyin, et al.
Publicado: (2012)

aPKCζ-dependent Repression of Yap is Necessary for Functional Restoration of Irradiated Salivary Glands with IGF-1
por: Chibly, Alejandro M., et al.
Publicado: (2018)

PKCζ as a promising therapeutic target for TNFα-induced inflammatory disorders in chronic cutaneous wounds
por: Zhang, Jian, et al.
Publicado: (2017)

Metformin attenuates the effect of Staphylococcus aureus on airway tight junctions by increasing PKCζ‐mediated phosphorylation of occludin
por: Kalsi, Kameljit K., et al.
Publicado: (2018)

Disaccharide-tag for highly sensitive identification of O-GlcNAc-modified proteins in mammalian cells
por: Abo, Hirohito, et al.
Publicado: (2022)

The Prognostic Impact of TGF-β1, Fascin, NF-κB and PKC-ζ Expression in Soft Tissue Sarcomas
por: Valkov, Andrej, et al.
Publicado: (2011)

FcαRI Dynamics Are Regulated by GSK-3 and PKCζ During Cytokine Mediated Inside-Out Signaling
por: ten Broeke, Toine, et al.
Publicado: (2019)

microRNA-25 targets PKCζ and protects osteoblastic cells from dexamethasone via activating AMPK signaling
por: Fan, Jian-bo, et al.
Publicado: (2016)

Retinoic acid directs breast cancer cell state changes through regulation of TET2-PKCζ pathway
por: Wu, M-J, et al.
Publicado: (2017)

Primary cilia control cell alignment and patterning in bone development via ceramide-PKCζ-β-catenin signaling
por: Lim, Jormay, et al.
Publicado: (2020)

Hengshun Aromatic Vinegar Ameliorates Vascular Endothelial Injury via Regulating PKCζ-Mediated Oxidative Stress and Apoptosis
por: Li, Xin, et al.
Publicado: (2021)

PKC-ζ mediated reduction of the extracellular vesicles-associated TGF-β1 overcomes radiotherapy resistance in breast cancer
por: Zhang, Fayun, et al.
Publicado: (2023)

Cdc42 and Par6–PKCζ regulate the spatially localized association of Dlg1 and APC to control cell polarization
por: Etienne-Manneville, Sandrine, et al.
Publicado: (2005)

Cannot write session to /tmp/vufind_sessions/sess_ltus9k936u8heqnvtqq28nanlr