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New therapies in nonmuscle invasive bladder cancer treatment

INTRODUCTION: Nonmuscle invasive bladder cancer (NMIBC) remains a very challenging disease to treat with high rates of recurrence and progression associated with current therapies. Recent technological and biological advances have led to the development of novel agents in NMIBC therapy. METHODS: We...

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Detalles Bibliográficos
Autores principales: Rayn, Kareem N., Hale, Graham R., Grave, Gustavo Pena-La, Agarwal, Piyush K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769243/
https://www.ncbi.nlm.nih.gov/pubmed/29343907
http://dx.doi.org/10.4103/iju.IJU_296_17
Descripción
Sumario:INTRODUCTION: Nonmuscle invasive bladder cancer (NMIBC) remains a very challenging disease to treat with high rates of recurrence and progression associated with current therapies. Recent technological and biological advances have led to the development of novel agents in NMIBC therapy. METHODS: We reviewed existing literature as well as currently active and recently completed clinical trials in NMIBC by querying PubMed.gov and clinicaltrials.gov. RESULTS: A wide variety of new therapies in NMIBC treatment are currently being developed, utilizing recent developments in the understanding of immune therapies and cancer biology. CONCLUSION: The ongoing efforts to develop new therapeutic approaches for NMIBC look very promising and are continuing to evolve.