Plasma virome of cattle from forest region revealed diverse small circular ssDNA viral genomes

BACKGROUND: Free-range cattle are common in the Northeast China area, which have close contact with farmers and may carry virus threatening to cattle and farmers. METHODS: Using viral metagenomics we analyzed the virome in plasma samples collected from 80 cattle from the forested region of Northeast...

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Autores principales: Wang, Hao, Li, Shouxin, Mahmood, Asif, Yang, Shixing, Wang, Xiaochun, Shen, Quan, Shan, Tongling, Deng, Xutao, Li, Jingjiao, Hua, Xiuguo, Cui, Li, Delwart, Eric, Zhang, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769433/
https://www.ncbi.nlm.nih.gov/pubmed/29334978
http://dx.doi.org/10.1186/s12985-018-0923-9
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author Wang, Hao
Li, Shouxin
Mahmood, Asif
Yang, Shixing
Wang, Xiaochun
Shen, Quan
Shan, Tongling
Deng, Xutao
Li, Jingjiao
Hua, Xiuguo
Cui, Li
Delwart, Eric
Zhang, Wen
author_facet Wang, Hao
Li, Shouxin
Mahmood, Asif
Yang, Shixing
Wang, Xiaochun
Shen, Quan
Shan, Tongling
Deng, Xutao
Li, Jingjiao
Hua, Xiuguo
Cui, Li
Delwart, Eric
Zhang, Wen
author_sort Wang, Hao
collection PubMed
description BACKGROUND: Free-range cattle are common in the Northeast China area, which have close contact with farmers and may carry virus threatening to cattle and farmers. METHODS: Using viral metagenomics we analyzed the virome in plasma samples collected from 80 cattle from the forested region of Northeast China. RESULTS: The virome of cattle plasma is composed of the viruses belonging to the families including Parvoviridae, Papillomaviridae, Picobirnaviridae, and divergent viral genomes showing sequence similarity to circular Rep-encoding single stranded (CRESS) DNA viruses. Five such CRESS-DNA genomes were full characterized, with Rep sequences related to circovirus and gemycircularvirus. Three bovine parvoviruses belonging to two different genera were also characterized. CONCLUSION: The virome in plasma samples of cattle from the forested region of Northeast China was revealed, which further characterized the diversity of viruses in cattle plasma. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12985-018-0923-9) contains supplementary material, which is available to authorized users.
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spelling pubmed-57694332018-01-25 Plasma virome of cattle from forest region revealed diverse small circular ssDNA viral genomes Wang, Hao Li, Shouxin Mahmood, Asif Yang, Shixing Wang, Xiaochun Shen, Quan Shan, Tongling Deng, Xutao Li, Jingjiao Hua, Xiuguo Cui, Li Delwart, Eric Zhang, Wen Virol J Research BACKGROUND: Free-range cattle are common in the Northeast China area, which have close contact with farmers and may carry virus threatening to cattle and farmers. METHODS: Using viral metagenomics we analyzed the virome in plasma samples collected from 80 cattle from the forested region of Northeast China. RESULTS: The virome of cattle plasma is composed of the viruses belonging to the families including Parvoviridae, Papillomaviridae, Picobirnaviridae, and divergent viral genomes showing sequence similarity to circular Rep-encoding single stranded (CRESS) DNA viruses. Five such CRESS-DNA genomes were full characterized, with Rep sequences related to circovirus and gemycircularvirus. Three bovine parvoviruses belonging to two different genera were also characterized. CONCLUSION: The virome in plasma samples of cattle from the forested region of Northeast China was revealed, which further characterized the diversity of viruses in cattle plasma. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12985-018-0923-9) contains supplementary material, which is available to authorized users. BioMed Central 2018-01-15 /pmc/articles/PMC5769433/ /pubmed/29334978 http://dx.doi.org/10.1186/s12985-018-0923-9 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Wang, Hao
Li, Shouxin
Mahmood, Asif
Yang, Shixing
Wang, Xiaochun
Shen, Quan
Shan, Tongling
Deng, Xutao
Li, Jingjiao
Hua, Xiuguo
Cui, Li
Delwart, Eric
Zhang, Wen
Plasma virome of cattle from forest region revealed diverse small circular ssDNA viral genomes
title Plasma virome of cattle from forest region revealed diverse small circular ssDNA viral genomes
title_full Plasma virome of cattle from forest region revealed diverse small circular ssDNA viral genomes
title_fullStr Plasma virome of cattle from forest region revealed diverse small circular ssDNA viral genomes
title_full_unstemmed Plasma virome of cattle from forest region revealed diverse small circular ssDNA viral genomes
title_short Plasma virome of cattle from forest region revealed diverse small circular ssDNA viral genomes
title_sort plasma virome of cattle from forest region revealed diverse small circular ssdna viral genomes
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769433/
https://www.ncbi.nlm.nih.gov/pubmed/29334978
http://dx.doi.org/10.1186/s12985-018-0923-9
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