The polycomb group protein EZH2 induces epithelial–mesenchymal transition and pluripotent phenotype of gastric cancer cells by binding to PTEN promoter

BACKGROUND: The influences of oncogenic Ezh2 on the progression and prognosis of gastric cancer (GC) and the underlying mechanisms are still poorly understood. Here, we aimed at investigating clinicopathological significance of Ezh2 in GC and the mechanisms underlying its function in GC development....

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Detalles Bibliográficos
Autores principales: Gan, Lu, Xu, Midie, Hua, Ruixi, Tan, Cong, Zhang, Jieyun, Gong, Yiwei, Wu, Zhenhua, Weng, Weiwei, Sheng, Weiqi, Guo, Weijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769437/
https://www.ncbi.nlm.nih.gov/pubmed/29335012
http://dx.doi.org/10.1186/s13045-017-0547-3

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