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Factors associated with poor treatment outcome of tuberculosis in Debre Tabor, northwest Ethiopia
OBJECTIVE: Directly observed treatment short course has been implemented as part of the national tuberculosis control program in Ethiopia. The strategy, as evidenced by different studies, has improved the survival and treatment success rate of tuberculosis patients. However, some patients failed to...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769532/ https://www.ncbi.nlm.nih.gov/pubmed/29335004 http://dx.doi.org/10.1186/s13104-018-3129-8 |
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author | Melese, Addisu Zeleke, Balew |
author_facet | Melese, Addisu Zeleke, Balew |
author_sort | Melese, Addisu |
collection | PubMed |
description | OBJECTIVE: Directly observed treatment short course has been implemented as part of the national tuberculosis control program in Ethiopia. The strategy, as evidenced by different studies, has improved the survival and treatment success rate of tuberculosis patients. However, some patients failed to complete their treatments and the factors for this failure were not assessed in the study area. We, therefore sought to identify factors associated with poor treatment outcome of tuberculosis in Debre Tabor, northwest Ethiopia. RESULTS: We included 303 patients (173 males, 130 females) with mean age of 34.9 years in the study and 39 (12.9%) patients were with poor treatment outcome over the period of 5 years (2008–2013). Being male, urban residency, positive and unknown smear result at the 2nd month of treatment and patients in the age of 35–44 years were more likely to have poor treatment outcomes than their counterparts. Patients in the new treatment category were less likely to have poor treatment outcome compared to the retreated cases. Further studies are recommended to explore the association of poor treatment outcome with other important factors which are not investigated by this study. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13104-018-3129-8) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-5769532 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-57695322018-01-25 Factors associated with poor treatment outcome of tuberculosis in Debre Tabor, northwest Ethiopia Melese, Addisu Zeleke, Balew BMC Res Notes Research Note OBJECTIVE: Directly observed treatment short course has been implemented as part of the national tuberculosis control program in Ethiopia. The strategy, as evidenced by different studies, has improved the survival and treatment success rate of tuberculosis patients. However, some patients failed to complete their treatments and the factors for this failure were not assessed in the study area. We, therefore sought to identify factors associated with poor treatment outcome of tuberculosis in Debre Tabor, northwest Ethiopia. RESULTS: We included 303 patients (173 males, 130 females) with mean age of 34.9 years in the study and 39 (12.9%) patients were with poor treatment outcome over the period of 5 years (2008–2013). Being male, urban residency, positive and unknown smear result at the 2nd month of treatment and patients in the age of 35–44 years were more likely to have poor treatment outcomes than their counterparts. Patients in the new treatment category were less likely to have poor treatment outcome compared to the retreated cases. Further studies are recommended to explore the association of poor treatment outcome with other important factors which are not investigated by this study. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13104-018-3129-8) contains supplementary material, which is available to authorized users. BioMed Central 2018-01-15 /pmc/articles/PMC5769532/ /pubmed/29335004 http://dx.doi.org/10.1186/s13104-018-3129-8 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Note Melese, Addisu Zeleke, Balew Factors associated with poor treatment outcome of tuberculosis in Debre Tabor, northwest Ethiopia |
title | Factors associated with poor treatment outcome of tuberculosis in Debre Tabor, northwest Ethiopia |
title_full | Factors associated with poor treatment outcome of tuberculosis in Debre Tabor, northwest Ethiopia |
title_fullStr | Factors associated with poor treatment outcome of tuberculosis in Debre Tabor, northwest Ethiopia |
title_full_unstemmed | Factors associated with poor treatment outcome of tuberculosis in Debre Tabor, northwest Ethiopia |
title_short | Factors associated with poor treatment outcome of tuberculosis in Debre Tabor, northwest Ethiopia |
title_sort | factors associated with poor treatment outcome of tuberculosis in debre tabor, northwest ethiopia |
topic | Research Note |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769532/ https://www.ncbi.nlm.nih.gov/pubmed/29335004 http://dx.doi.org/10.1186/s13104-018-3129-8 |
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