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SHP-2 restricts apoptosis induced by chemotherapeutic agents via Parkin-dependent autophagy in cervical cancer

BACKGROUND: Autophagy is a cell degradation pathway that eliminates damaged or unwanted proteins and organelles. Autophagy protects cells from chemotherapeutic agents by scavenging damaged mitochondria. METHODS: Plasmid transfection and shRNA were used to regulate SHP-2 expression. Annexin V/PI stai...

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Detalles Bibliográficos
Autores principales:	Yan, Dewen, Zhu, Danyang, Zhao, Xiumin, Su, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769549/ https://www.ncbi.nlm.nih.gov/pubmed/29371831 http://dx.doi.org/10.1186/s12935-018-0505-3

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