Early neonatal loss of inhibitory synaptic input to the spinal motor neurons confers spina bifida-like leg dysfunction in a chicken model

Spina bifida aperta (SBA), one of the most common congenital malformations, causes lifelong neurological complications, particularly in terms of motor dysfunction. Fetuses with SBA exhibit voluntary leg movements in utero and during early neonatal life, but these disappear within the first few weeks...

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Detalles Bibliográficos
Autores principales: Khan, Md. Sakirul Islam, Nabeka, Hiroaki, Islam, Farzana, Shimokawa, Tetsuya, Saito, Shouichiro, Li, Xuan, Kawabe, Soichiro, Hamada, Fumihiko, Tachibana, Tetsuya, Matsuda, Seiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769610/
https://www.ncbi.nlm.nih.gov/pubmed/28982681
http://dx.doi.org/10.1242/dmm.031054

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