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Systemic HIV-1 infection produces a unique glial footprint in humanized mouse brains
Studies of innate glial cell responses for progressive human immunodeficiency virus type one (HIV-1) infection are limited by a dearth of human disease-relevant small-animal models. To overcome this obstacle, newborn NOD/SCID/IL2Rγc(−/−) (NSG) mice were reconstituted with a humanized brain and immun...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769612/ https://www.ncbi.nlm.nih.gov/pubmed/29084769 http://dx.doi.org/10.1242/dmm.031773 |