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Lyplal1 is dispensable for normal fat deposition in mice

Genome-wide association studies (GWAS) have detected association between variants in or near the Lysophospholipase-like 1 (LYPLAL1) locus and metabolic traits, including central obesity, fatty liver and waist-to-hip ratio. LYPLAL1 is also known to be upregulated in the adipose tissue of obese patien...

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Detalles Bibliográficos
Autores principales: Watson, Rachel A., Gates, Amy S., Wynn, Elizabeth H., Calvert, Fiona E., Girousse, Amandine, Lelliott, Christopher J., Barroso, Inês
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769613/
https://www.ncbi.nlm.nih.gov/pubmed/29084768
http://dx.doi.org/10.1242/dmm.031864