A stepwise model of reaction-diffusion and positional information governs self-organized human peri-gastrulation-like patterning

How position-dependent cell fate acquisition occurs during embryogenesis is a central question in developmental biology. To study this process, we developed a defined, high-throughput assay to induce peri-gastrulation-associated patterning in geometrically confined human pluripotent stem cell (hPSC)...

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Detalles Bibliográficos
Autores principales: Tewary, Mukul, Ostblom, Joel, Prochazka, Laura, Zulueta-Coarasa, Teresa, Shakiba, Nika, Fernandez-Gonzalez, Rodrigo, Zandstra, Peter W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Human Development
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769627/
https://www.ncbi.nlm.nih.gov/pubmed/28870989
http://dx.doi.org/10.1242/dev.149658

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769627/
https://www.ncbi.nlm.nih.gov/pubmed/28870989
http://dx.doi.org/10.1242/dev.149658

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