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High resolution ultrasonography of the tibial nerve in diabetic peripheral neuropathy

AIM OF THE STUDY: High-resolution ultrasonography of the tibial nerve is a fast and non invasive tool for diagnosis of diabetic peripheral neuropathy. Our study was aimed at finding out the correlation of the cross sectional area and maximum thickness of nerve fascicles of the tibial nerve with the...

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Autores principales: Singh, Kunwarpal, Gupta1, Kamlesh, Kaur, Sukhdeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medical Communications Sp. z o.o. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769664/
https://www.ncbi.nlm.nih.gov/pubmed/29375899
http://dx.doi.org/10.15557/JoU.2017.0036
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author Singh, Kunwarpal
Gupta1, Kamlesh
Kaur, Sukhdeep
author_facet Singh, Kunwarpal
Gupta1, Kamlesh
Kaur, Sukhdeep
author_sort Singh, Kunwarpal
collection PubMed
description AIM OF THE STUDY: High-resolution ultrasonography of the tibial nerve is a fast and non invasive tool for diagnosis of diabetic peripheral neuropathy. Our study was aimed at finding out the correlation of the cross sectional area and maximum thickness of nerve fascicles of the tibial nerve with the presence and severity of diabetic peripheral neuropathy. MATERIAL AND METHODS: 75 patients with type 2 diabetes mellitus clinically diagnosed with diabetic peripheral neuropathy were analysed, and the severity of neuropathy was determined using the Toronto Clinical Neuropathy Score. 58 diabetic patients with no clinical suspicion of diabetic peripheral neuropathy and 75 healthy non-diabetic subjects were taken as controls. The cross sectional area and maximum thickness of nerve fascicles of the tibial nerves were calculated 3 cm cranial to the medial malleolus in both lower limbs. RESULTS: The mean cross sectional area (22.63 +/− 2.66 mm(2)) and maximum thickness of nerve fascicles (0.70 mm) of the tibial nerves in patients with diabetic peripheral neuropathy compared with both control groups was significantly larger, and statistically significant correlation was found with the Toronto Clinical Neuropathy Score (p < 0.001). The diabetic patients with no signs of peripheral neuropathy had a larger mean cross sectional area (14.40 +/− 1.72 mm(2)) and maximum thickness of nerve fascicles of the tibial nerve (0.40 mm) than healthy non-diabetic subjects (12.42 +/− 1.01 mm(2) and 0.30 mm respectively). CONCLUSION: The cross sectional area and maximum thickness of nerve fascicles of the tibial nerve is larger in diabetic patients with or without peripheral neuropathy than in healthy control subjects, and ultrasonography can be used as a good screening tool in these patients.
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spelling pubmed-57696642018-01-28 High resolution ultrasonography of the tibial nerve in diabetic peripheral neuropathy Singh, Kunwarpal Gupta1, Kamlesh Kaur, Sukhdeep J Ultrason Original Paper AIM OF THE STUDY: High-resolution ultrasonography of the tibial nerve is a fast and non invasive tool for diagnosis of diabetic peripheral neuropathy. Our study was aimed at finding out the correlation of the cross sectional area and maximum thickness of nerve fascicles of the tibial nerve with the presence and severity of diabetic peripheral neuropathy. MATERIAL AND METHODS: 75 patients with type 2 diabetes mellitus clinically diagnosed with diabetic peripheral neuropathy were analysed, and the severity of neuropathy was determined using the Toronto Clinical Neuropathy Score. 58 diabetic patients with no clinical suspicion of diabetic peripheral neuropathy and 75 healthy non-diabetic subjects were taken as controls. The cross sectional area and maximum thickness of nerve fascicles of the tibial nerves were calculated 3 cm cranial to the medial malleolus in both lower limbs. RESULTS: The mean cross sectional area (22.63 +/− 2.66 mm(2)) and maximum thickness of nerve fascicles (0.70 mm) of the tibial nerves in patients with diabetic peripheral neuropathy compared with both control groups was significantly larger, and statistically significant correlation was found with the Toronto Clinical Neuropathy Score (p < 0.001). The diabetic patients with no signs of peripheral neuropathy had a larger mean cross sectional area (14.40 +/− 1.72 mm(2)) and maximum thickness of nerve fascicles of the tibial nerve (0.40 mm) than healthy non-diabetic subjects (12.42 +/− 1.01 mm(2) and 0.30 mm respectively). CONCLUSION: The cross sectional area and maximum thickness of nerve fascicles of the tibial nerve is larger in diabetic patients with or without peripheral neuropathy than in healthy control subjects, and ultrasonography can be used as a good screening tool in these patients. Medical Communications Sp. z o.o. 2017-12-29 2017-12 /pmc/articles/PMC5769664/ /pubmed/29375899 http://dx.doi.org/10.15557/JoU.2017.0036 Text en 2017 Polish Ultrasound Society. Published by Medical Communications Sp. z o.o. All rights reserved. http://creativecommons.org/licenses/by-nc-nd This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (CC BY-NC-ND). Reproduction is permitted for personal, educational, non-commercial use, provided that the original article is in whole, unmodified, and properly cited.
spellingShingle Original Paper
Singh, Kunwarpal
Gupta1, Kamlesh
Kaur, Sukhdeep
High resolution ultrasonography of the tibial nerve in diabetic peripheral neuropathy
title High resolution ultrasonography of the tibial nerve in diabetic peripheral neuropathy
title_full High resolution ultrasonography of the tibial nerve in diabetic peripheral neuropathy
title_fullStr High resolution ultrasonography of the tibial nerve in diabetic peripheral neuropathy
title_full_unstemmed High resolution ultrasonography of the tibial nerve in diabetic peripheral neuropathy
title_short High resolution ultrasonography of the tibial nerve in diabetic peripheral neuropathy
title_sort high resolution ultrasonography of the tibial nerve in diabetic peripheral neuropathy
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769664/
https://www.ncbi.nlm.nih.gov/pubmed/29375899
http://dx.doi.org/10.15557/JoU.2017.0036
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