Cargando…

Mechanistic implications of enhanced editing by a HyperTRIBE RNA-binding protein

We previously developed TRIBE, a method for the identification of cell-specific RNA-binding protein targets. TRIBE expresses an RBP of interest fused to the catalytic domain (cd) of the RNA-editing enzyme ADAR and performs adenosine-to-inosine editing on RNA targets of the RBP. However, target ident...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Weijin, Rahman, Reazur, Rosbash, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769745/
https://www.ncbi.nlm.nih.gov/pubmed/29127211
http://dx.doi.org/10.1261/rna.064691.117

Ejemplares similares