Synthesis and anti-myocarditis activity in a multifunctional lanthanide microporous metal-organic framework with 1D helical chain building units

A new microporous lanthanide metal-organic framework, {[Yb(BTB)(H(2)O) (DEF)(2)}(n) (1, DEF=N,N-Diethylformamide), with 1D nano-sized channels has been constructed by bridging helical chain secondary building units with 1,3,5-benzenetrisbenzoic acid (H(3)BTB) ligand. Structural characterization sugg...

Descripción completa

Detalles Bibliográficos
Autores principales: Hong, Chenglv, Zhou, Xinlang, Huang, Weijian, Shan, Peiren, Dong, Fengquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769762/
https://www.ncbi.nlm.nih.gov/pubmed/29340528
http://dx.doi.org/10.1590/1414-431X20177050
_version_ 1783292956112846848
author Hong, Chenglv
Zhou, Xinlang
Huang, Weijian
Shan, Peiren
Dong, Fengquan
author_facet Hong, Chenglv
Zhou, Xinlang
Huang, Weijian
Shan, Peiren
Dong, Fengquan
author_sort Hong, Chenglv
collection PubMed
description A new microporous lanthanide metal-organic framework, {[Yb(BTB)(H(2)O) (DEF)(2)}(n) (1, DEF=N,N-Diethylformamide), with 1D nano-sized channels has been constructed by bridging helical chain secondary building units with 1,3,5-benzenetrisbenzoic acid (H(3)BTB) ligand. Structural characterization suggests that this complex crystallizes in the hexagonal space group P6(1)22 and possesses 1D triangular channels with coordinated water molecules pointing to the channel center. In addition, anti-myocarditis properties of compound 1 were evaluated in vivo. The results showed that compound 1 can improve hemodynamic parameters of, and it may be a good therapeutic option for heart failure in the future.
format Online
Article
Text
id pubmed-5769762
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Associação Brasileira de Divulgação Científica
record_format MEDLINE/PubMed
spelling pubmed-57697622018-01-31 Synthesis and anti-myocarditis activity in a multifunctional lanthanide microporous metal-organic framework with 1D helical chain building units Hong, Chenglv Zhou, Xinlang Huang, Weijian Shan, Peiren Dong, Fengquan Braz J Med Biol Res Research Articles A new microporous lanthanide metal-organic framework, {[Yb(BTB)(H(2)O) (DEF)(2)}(n) (1, DEF=N,N-Diethylformamide), with 1D nano-sized channels has been constructed by bridging helical chain secondary building units with 1,3,5-benzenetrisbenzoic acid (H(3)BTB) ligand. Structural characterization suggests that this complex crystallizes in the hexagonal space group P6(1)22 and possesses 1D triangular channels with coordinated water molecules pointing to the channel center. In addition, anti-myocarditis properties of compound 1 were evaluated in vivo. The results showed that compound 1 can improve hemodynamic parameters of, and it may be a good therapeutic option for heart failure in the future. Associação Brasileira de Divulgação Científica 2018-01-11 /pmc/articles/PMC5769762/ /pubmed/29340528 http://dx.doi.org/10.1590/1414-431X20177050 Text en https://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Articles
Hong, Chenglv
Zhou, Xinlang
Huang, Weijian
Shan, Peiren
Dong, Fengquan
Synthesis and anti-myocarditis activity in a multifunctional lanthanide microporous metal-organic framework with 1D helical chain building units
title Synthesis and anti-myocarditis activity in a multifunctional lanthanide microporous metal-organic framework with 1D helical chain building units
title_full Synthesis and anti-myocarditis activity in a multifunctional lanthanide microporous metal-organic framework with 1D helical chain building units
title_fullStr Synthesis and anti-myocarditis activity in a multifunctional lanthanide microporous metal-organic framework with 1D helical chain building units
title_full_unstemmed Synthesis and anti-myocarditis activity in a multifunctional lanthanide microporous metal-organic framework with 1D helical chain building units
title_short Synthesis and anti-myocarditis activity in a multifunctional lanthanide microporous metal-organic framework with 1D helical chain building units
title_sort synthesis and anti-myocarditis activity in a multifunctional lanthanide microporous metal-organic framework with 1d helical chain building units
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769762/
https://www.ncbi.nlm.nih.gov/pubmed/29340528
http://dx.doi.org/10.1590/1414-431X20177050
work_keys_str_mv AT hongchenglv synthesisandantimyocarditisactivityinamultifunctionallanthanidemicroporousmetalorganicframeworkwith1dhelicalchainbuildingunits
AT zhouxinlang synthesisandantimyocarditisactivityinamultifunctionallanthanidemicroporousmetalorganicframeworkwith1dhelicalchainbuildingunits
AT huangweijian synthesisandantimyocarditisactivityinamultifunctionallanthanidemicroporousmetalorganicframeworkwith1dhelicalchainbuildingunits
AT shanpeiren synthesisandantimyocarditisactivityinamultifunctionallanthanidemicroporousmetalorganicframeworkwith1dhelicalchainbuildingunits
AT dongfengquan synthesisandantimyocarditisactivityinamultifunctionallanthanidemicroporousmetalorganicframeworkwith1dhelicalchainbuildingunits

Ejemplares similares