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YAP repression of the WNT3 gene controls hESC differentiation along the cardiac mesoderm lineage

Activin/SMAD signaling in human embryonic stem cells (hESCs) ensures NANOG expression and stem cell pluripotency. In the presence of Wnt ligand, the Activin/SMAD transcription network switches to cooperate with Wnt/β-catenin and induce mesendodermal (ME) differentiation genes. We show here that the...

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Detalles Bibliográficos
Autores principales:	Estarás, Conchi, Hsu, Hui-Ting, Huang, Ling, Jones, Katherine A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769769/ https://www.ncbi.nlm.nih.gov/pubmed/29269485 http://dx.doi.org/10.1101/gad.307512.117

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