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The HoxD cluster is a dynamic and resilient TAD boundary controlling the segregation of antagonistic regulatory landscapes

The mammalian HoxD cluster lies between two topologically associating domains (TADs) matching distinct enhancer-rich regulatory landscapes. During limb development, the telomeric TAD controls the early transcription of Hoxd genes in forearm cells, whereas the centromeric TAD subsequently regulates m...

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Detalles Bibliográficos
Autores principales:	Rodríguez-Carballo, Eddie, Lopez-Delisle, Lucille, Zhan, Ye, Fabre, Pierre J., Beccari, Leonardo, El-Idrissi, Imane, Huynh, Thi Hanh Nguyen, Ozadam, Hakan, Dekker, Job, Duboule, Denis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769770/ https://www.ncbi.nlm.nih.gov/pubmed/29273679 http://dx.doi.org/10.1101/gad.307769.117

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