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Sost Deficiency does not Alter Bone’s Lacunar or Vascular Porosity in Mice

SCLEROSTIN (Sost) is expressed predominantly in osteocytes acting as a negative regulator of bone formation. In humans, mutations in the SOST gene lead to skeletal overgrowth and increased bone mineral density, suggesting that SCLEROSTIN is a key regulator of bone mass. The function of SCLEROSTIN as...

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Detalles Bibliográficos
Autores principales:	Mosey, Henry, Núñez, Juan A., Goring, Alice, Clarkin, Claire E., Staines, Katherine A., Lee, Peter D., Pitsillides, Andrew A., Javaheri, Behzad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769812/ https://www.ncbi.nlm.nih.gov/pubmed/29349060 http://dx.doi.org/10.3389/fmats.2017.00027

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