Cargando…
Structural Analysis of Recombinant Human Preproinsulins by Structure Prediction, Molecular Dynamics, and Protein-Protein Docking
More effective production of human insulin is important, because insulin is the main medication that is used to treat multiple types of diabetes and because many people are suffering from diabetes. The current system of insulin production is based on recombinant DNA technology, and the expression ve...
Autores principales: | Jung, Sung Hun, Kim, Chang-Kyu, Lee, Gunhee, Yoon, Jonghwan, Lee, Minho |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society of Gastrointestinal Intervention
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769858/ https://www.ncbi.nlm.nih.gov/pubmed/29307140 http://dx.doi.org/10.5808/GI.2017.15.4.142 |
Ejemplares similares
-
Identification of New Potential APE1 Inhibitors by Pharmacophore Modeling and Molecular Docking
por: Lee, In Won, et al.
Publicado: (2017) -
The NH2 terminus of preproinsulin directs the translocation and glycosylation of a bacterial cytoplasmic protein by mammalian microsomal membranes
Publicado: (1986) -
Prevention of Diabetes in the NOD Mouse by Intra-muscular Injection of Recombinant Adeno-associated Virus Containing the Preproinsulin II Gene
por: Jindal, Rahul M., et al.
Publicado: (2001) -
Impaired Cleavage of Preproinsulin Signal Peptide Linked to Autosomal-Dominant Diabetes
por: Liu, Ming, et al.
Publicado: (2012) -
Human islet T cells are highly reactive to preproinsulin in type 1 diabetes
por: Anderson, Amanda M., et al.
Publicado: (2021)