Anti-angiogenic drug loaded liposomes: Nanotherapy for early atherosclerotic lesions in mice

Fumagillin-loaded liposomes were injected into ApoE-KO mice. The animals were divided into several groups to test the efficacy of this anti-angiogenic drug for early treatment of atherosclerotic lesions. Statistical analysis of the lesions revealed a decrease in the lesion size after 5 weeks of trea...

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Autores principales: Pont, Isabel, Calatayud-Pascual, Aracely, López-Castellano, Alicia, Albelda, Elena P., García-España, Enrique, Martí-Bonmatí, Luis, Frias, Juan C., Albelda, M. Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770017/
https://www.ncbi.nlm.nih.gov/pubmed/29338009
http://dx.doi.org/10.1371/journal.pone.0190540
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author Pont, Isabel
Calatayud-Pascual, Aracely
López-Castellano, Alicia
Albelda, Elena P.
García-España, Enrique
Martí-Bonmatí, Luis
Frias, Juan C.
Albelda, M. Teresa
author_facet Pont, Isabel
Calatayud-Pascual, Aracely
López-Castellano, Alicia
Albelda, Elena P.
García-España, Enrique
Martí-Bonmatí, Luis
Frias, Juan C.
Albelda, M. Teresa
author_sort Pont, Isabel
collection PubMed
description Fumagillin-loaded liposomes were injected into ApoE-KO mice. The animals were divided into several groups to test the efficacy of this anti-angiogenic drug for early treatment of atherosclerotic lesions. Statistical analysis of the lesions revealed a decrease in the lesion size after 5 weeks of treatment.
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spelling pubmed-57700172018-01-23 Anti-angiogenic drug loaded liposomes: Nanotherapy for early atherosclerotic lesions in mice Pont, Isabel Calatayud-Pascual, Aracely López-Castellano, Alicia Albelda, Elena P. García-España, Enrique Martí-Bonmatí, Luis Frias, Juan C. Albelda, M. Teresa PLoS One Research Article Fumagillin-loaded liposomes were injected into ApoE-KO mice. The animals were divided into several groups to test the efficacy of this anti-angiogenic drug for early treatment of atherosclerotic lesions. Statistical analysis of the lesions revealed a decrease in the lesion size after 5 weeks of treatment. Public Library of Science 2018-01-16 /pmc/articles/PMC5770017/ /pubmed/29338009 http://dx.doi.org/10.1371/journal.pone.0190540 Text en © 2018 Pont et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Pont, Isabel
Calatayud-Pascual, Aracely
López-Castellano, Alicia
Albelda, Elena P.
García-España, Enrique
Martí-Bonmatí, Luis
Frias, Juan C.
Albelda, M. Teresa
Anti-angiogenic drug loaded liposomes: Nanotherapy for early atherosclerotic lesions in mice
title Anti-angiogenic drug loaded liposomes: Nanotherapy for early atherosclerotic lesions in mice
title_full Anti-angiogenic drug loaded liposomes: Nanotherapy for early atherosclerotic lesions in mice
title_fullStr Anti-angiogenic drug loaded liposomes: Nanotherapy for early atherosclerotic lesions in mice
title_full_unstemmed Anti-angiogenic drug loaded liposomes: Nanotherapy for early atherosclerotic lesions in mice
title_short Anti-angiogenic drug loaded liposomes: Nanotherapy for early atherosclerotic lesions in mice
title_sort anti-angiogenic drug loaded liposomes: nanotherapy for early atherosclerotic lesions in mice
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770017/
https://www.ncbi.nlm.nih.gov/pubmed/29338009
http://dx.doi.org/10.1371/journal.pone.0190540
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